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Description

We found that treating HG-3 and MEC-1 cells with CB-839 increased LC3-I to LC3-II protein conversion and p62 protein degradation ( Figure 4A )

Proc Natl Acad Sci USA 1985

Doi: Barone, Eugenio, Elizabeth Head, D

Safety and efficacy for this formulation have not been evaluated by the FDA

Regarding hydrophobic bonds, the ligands were bound to the following residues of GPx4: Ile22, Val57, Ala61, Phe78, Ala94, Tyr96, Ile129, Leu130, Ala133, Trp136, Pro155, and Met156 for Ferrostatin